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Rabbit anti-Human NUBP2 Polyclonal Antibody

The antibody against NUBP2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 142-271 of human NUBP2 (NP_036357.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-08732A

The antibody against NUBP2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 142-271 of human NUBP2 (NP_036357.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-08732A ClonalityPolyclonal
Host SpeciesRabbitTarget NameNUBP2
Target SynonymsCFD1; CIAO6; NBP 2; NUBP1; NUBP2FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesNIH/3T3, HepG2, LO2, Mouse brain, Mouse lung, Rat liverApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 142-271 of human NUBP2 (NP_036357.1).Target SpeciesHuman
Immunogen SequenceMATIEALRPYQPLGALVVTTPQAVSVGDVRRELTFCRKTGLRVMGIVENMSGFTCPHCTECTSVFSRGGGEELAQLAGVPFLGSVPLDPALMRTLEEGHDFIQEFPGSPAFAALTSIAQKILDATPACLPUniprot IDQ9Y5Y2
Background Information
  • Uniprot Id

    Q9Y5Y2

  • Target Species

    Human

  • Target Name

    NUBP2

  • Target Full Name

    Cytosolic Fe-S cluster assembly factor NUBP2

  • Target Function

    Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Negatively regulates cilium formation and structure.

  • Target Subcellular Location

    Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, microtubule organizing center.

  • Target Protein Families

    Mrp/NBP35 ATP-binding proteins family, NUBP2/CFD1 subfamily

  • Target Tissue Specificity

    Widely expressed with highest expression in skeletal muscle.

  • Target Synonyms

    C447E6.1 (nucleotide binding protein 1 (E.coli MinD like) ); CFD1; Cytosolic Fe-S cluster assembly factor NUBP2; D17Wsu11e; Homolog of yeast cytosolic FeS cluster deficient 1; NBP 2; NUBP1; Nubp2; NUBP2_HUMAN; Nucleotide binding protein 2 (E.coli MinD like); Nucleotide binding protein 2 (MinD homolog, E. coli); Nucleotide binding protein 2; Nucleotide-binding protein 2

  • Target Background

    This gene encodes an adenosine triphosphate (ATP) and metal-binding protein that is required for the assembly of cyotosolic iron-sulfur proteins. The encoded protein functions in a heterotetramer with nucleotide-binding protein 1 (NUBP1). Alternative splicing results in multiple transcript variants.

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