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The antibody against NUCKS1 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human NUCKS. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on IHC, ELISA.
The antibody against NUCKS1 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human NUCKS. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on IHC, ELISA.
$167.00
| Cat.No | ADC-34111A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NUCKS1 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human NUCKS. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9H1E3 |
Uniprot Id
Q9H1E3
Target Species
Human
Target Name
NUCKS1
Target Full Name
Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1
Target Function
Chromatin-associated protein involved in DNA repair by promoting homologous recombination (HR). Binds double-stranded DNA (dsDNA) and secondary DNA structures, such as D-loop structures, but with less affinity than RAD51AP1.
Target Subcellular Location
Nucleus. Chromosome.
Target Tissue Specificity
Widely expressed, with highest levels in thyroid gland, prostate and uterus and in fetal liver, thymus and lung.
Target Synonyms
FLJ21480; FLJ32016; FLJ38536; JC7; NUCKS 1; NUCKS; NUCKS_HUMAN; Nucks1; Nuclear casein kinase and cyclin dependent kinase substrate 1; Nuclear ubiquitous casein and cyclin dependent kinases substrate; Nuclear ubiquitous casein and cyclin-dependent kinases substrate; Nuclear ubiquitous casein kinase and cyclin dependent kinase substrate; P1; Potential LAG1 interactor
Target Background
This gene encodes a nuclear protein that is highly conserved in vertebrates. The conserved regions of the protein contain several consensus phosphorylation sites for casein kinase II and cyclin-dependent kinases, two putative nuclear localization signals, and a basic DNA-binding domain. It is phosphorylated in vivo by Cdk1 during mitosis of the cell cycle.
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