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The antibody against NUDT18 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-323 of human NUDT18 (NP_079091.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against NUDT18 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-323 of human NUDT18 (NP_079091.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-01222A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NUDT18 |
| Target Synonyms | MTH3; NUDT18 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | MCF7 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-323 of human NUDT18 (NP_079091.3). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q6ZVK8 | Immunogen Sequence |
Uniprot Id
Q6ZVK8
Target Species
Human
Target Name
NUDT18
Target Full Name
8-oxo-dGDP phosphatase NUDT18
Target Function
Mediates the hydrolysis of oxidized nucleoside diphosphate derivatives. Hydrolyzes 8-oxo-7,8-dihydroguanine (8-oxo-Gua)-containing deoxyribo- and ribonucleoside diphosphates to the monophosphates. Hydrolyzes 8-oxo-dGDP and 8-oxo-GDP with the same efficiencies. Hydrolyzes also 8-OH-dADP and 2-OH-dADP. Exhibited no or minimal hydrolysis activity against 8-oxo-dGTP, 8-oxo-GTP, dGTP, GTP, dGDP and GDP. Probably removes oxidized guanine nucleotides from both the DNA and RNA precursor pools.
Target Protein Families
Nudix hydrolase family
Target Synonyms
2-hydroxy-dADP phosphatase; 7,8-dihydro-8-oxoguanine phosphatase; 8-oxo-dGDP phosphatase NUDT18; BC036718; FLJ22494; MGC38179; MTH3; mutT homolog 3; mutT human homolog 3; Nucleoside diphosphate linked moiety X motif 18; Nucleoside diphosphate-linked moiety X motif 18; NUD18_HUMAN; Nudix (nucleoside diphosphate linked moiety X) type motif 18; Nudix motif 18; NUDT 18; Nudt18; RGD1311802
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