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Rabbit anti-Human NUDT19 Monoclonal Antibody

The antibody against NUDT19 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 60-190 of human NUDT19 (A8MXV4) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.

ADA-13404A

The antibody against NUDT19 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 60-190 of human NUDT19 (A8MXV4) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.

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Specifications


Cat.No ADA-13404A ClonalityMonoclonal
Host SpeciesRabbitTarget NameNUDT19
Target SynonymsRP2; NUDT19FormLiquid
Species ReactivityHuman, RatIsotypeIgG
Storage Buffer50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesRat heart, 293T, Jurkat, K-562ApplicationELISA, WB, IF/ICC, IHC-P

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 60-190 of human NUDT19 (A8MXV4).Target SpeciesHuman
Immunogen SequenceHVFSGGVLDAADRSADWLGLFAPHHGPPRFGLGPAPFSRTAFPSLPDTDDHKTDNTGTLPEDVAFRICAVREAFEEAGVLLLRPRTSPPGPAPGPGLALEPPPGLASWRDRVRQDPRHFLRLCAHLDCTPDUniprot IDA8MXV4
Background Information
  • Uniprot Id

    A8MXV4

  • Target Species

    Human

  • Target Name

    NUDT19

  • Target Full Name

    Acyl-coenzyme A diphosphatase NUDT19

  • Target Function

    Fatty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatty acyl-CoA to yield acyl-4'-phosphopantetheine and adenosine 3',5'-bisphosphate. Mediates the hydrolysis of a wide range of CoA esters, including choloyl-CoA and branched-chain fatty-acyl-CoA esters and at low substrate concentrations medium and long-chain fatty-acyl-CoA esters are the primary substrates. Highest activity seen with medium-chain acyl-CoA esters and higher rates of activity seen with the unsaturated acyl-CoA esters compared with the saturated esters. Exhibits decapping activity towards dpCoA-capped RNAs in vitro.

  • Target Subcellular Location

    Peroxisome.

  • Target Protein Families

    Nudix hydrolase family

  • Target Synonyms

    mitochondrial; Nucleoside diphosphate-linked moiety X motif 19; nucleoside diphosphate-linked moiety X motif 19, mitochondrial; NUD19_HUMAN; nudix (nucleoside diphosphate linked moiety X)-type motif 19; Nudix motif 19; NUDT19; RP2

  • Target Background

    Predicted to enable magnesium ion binding activity. Predicted to be involved in purine nucleoside bisphosphate metabolic process. Predicted to be located in cytosol and peroxisomal matrix.

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