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Rabbit anti-Human NUP43 Polyclonal Antibody

The antibody against NUP43 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 150-260 of human NUP43 (NP_942590.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-04698A

The antibody against NUP43 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 150-260 of human NUP43 (NP_942590.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-04698A ClonalityPolyclonal
Host SpeciesRabbitTarget NameNUP43
Target Synonymsp42; bA350J20.1; NUP43FormLiquid
Species ReactivityHuman, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesHeLa, OVCAR3, Rat spleen, Rat testisApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 150-260 of human NUP43 (NP_942590.1).Target SpeciesHuman
Immunogen SequenceDGRINLFRADHKEAVRTIDNADSSTLHAVTFLRTPEILTVNSIGQLKIWDFRQQGNEPSQILSLTGDRVPLHCVDRHPNQQHVVATGGQDGMLSIWDVRQGTMPVSLLKAHUniprot IDQ8NFH3
Background Information
  • Uniprot Id

    Q8NFH3

  • Target Species

    Human

  • Target Name

    NUP43

  • Target Full Name

    Nucleoporin Nup43

  • Target Function

    Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation.

  • Target Subcellular Location

    Chromosome, centromere, kinetochore. Nucleus, nuclear pore complex.

  • Target Synonyms

    NUP43Nucleoporin Nup43; Nup107-160 subcomplex subunit Nup43; p42

  • Target Background

    Bidirectional transport of macromolecules between the cytoplasm and nucleus occurs through nuclear pore complexes (NPCs) embedded in the nuclear envelope. NPCs are composed of subcomplexes, and NUP43 is part of one such subcomplex, Nup107-160 (Loiodice et al., 2004 [PubMed 15146057]).

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