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Rabbit anti-Human NVL Polyclonal Antibody

The antibody against NVL was raised in rabbit using the Synthesized peptide derived from the Internal region of Human NVL. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.

ADC-37299A

The antibody against NVL was raised in rabbit using the Synthesized peptide derived from the Internal region of Human NVL. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.

$167.00

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Specifications


Cat.No ADC-37299A ClonalityPolyclonal
Host SpeciesRabbitTarget NameNVL
FormLiquidSpecies ReactivityHuman, Mouse, Rat
IsotypeIgGStorage Buffer0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol
Purification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.ConjugateNon-conjugated
ApplicationELISA, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from the Internal region of Human NVL.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDO15381
Background Information
  • Uniprot Id

    O15381

  • Target Species

    Human

  • Target Name

    NVL

  • Target Full Name

    Nuclear valosin-containing protein-like

  • Target Function

    Participates in the assembly of the telomerase holoenzyme and effecting of telomerase activity via its interaction with TERT. Involved in both early and late stages of the pre-rRNA processing pathways. Spatiotemporally regulates 60S ribosomal subunit biogenesis in the nucleolus. Catalyzes the release of specific assembly factors, such as WDR74, from pre-60S ribosomal particles through the ATPase activity.

  • Target Subcellular Location

    [Isoform 2]: Nucleus, nucleoplasm.; [Isoform 1]: Nucleus, nucleolus. Nucleus, nucleoplasm.

  • Target Protein Families

    AAA ATPase family

  • Target Tissue Specificity

    Widely expressed. Highest level of expression in heart, placenta, skeletal muscle, pancreas and retina.

  • Target Synonyms

    Nuclear valosin containing protein like; Nuclear valosin-containing protein-like; Nuclear VCP like; Nuclear VCP-like protein; Nvl; NVL_HUMAN; NVLp; OTTHUMP00000035641; OTTHUMP00000216593; OTTHUMP00000216594; OTTHUMP00000216599; OTTHUMP00000216600

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