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Rabbit anti-Human OGFR Polyclonal Antibody

The antibody against OGFR was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human OGFR (NP_031372.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.

ADA-11055A

The antibody against OGFR was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human OGFR (NP_031372.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.

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Specifications


Cat.No ADA-11055A ClonalityPolyclonal
Host SpeciesRabbitTarget NameOGFR
Target SynonymsOGFRFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.05% proclin300, pH7.3.Purification MethodAffinity purification
Positive SamplesRat brain, A-549, HepG2, Mouse brain, Mouse lungApplicationELISA, WB, IF/ICC, IHC-P

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human OGFR (NP_031372.2).Target SpeciesHuman
Uniprot IDQ9NZT2Immunogen Sequence
Background Information
  • Uniprot Id

    Q9NZT2

  • Target Species

    Human

  • Target Name

    OGFR

  • Target Full Name

    Opioid growth factor receptor

  • Target Function

    Receptor for opioid growth factor (OGF), also known as Met-enkephalin. Seems to be involved in growth regulation.

  • Target Subcellular Location

    Cytoplasm. Nucleus. Note=The OGF/OGFR complex is probably translocated to the nucleus.

  • Target Protein Families

    Opioid growth factor receptor family

  • Target Tissue Specificity

    Highly expressed in the heart and liver, moderately in skeletal muscle and kidney and to a lesser extent in brain and pancreas. Expressed in fetal tissues including liver and kidney.

  • Target Research Area

    Cell Biology

  • Target Synonyms

    7 60 protein; HGNC:15768; Met enkephalin receptor; OGFr; OGFR_HUMAN; Opioid growth factor receptor; Protein 7-60; Zeta Opioid Receptor; Zeta type opioid receptor; Zeta-type opioid receptor

  • Target Background

    The protein encoded by this gene is a receptor for opioid growth factor (OGF), also known as [Met(5)]-enkephalin. OGF is a negative regulator of cell proliferation and tissue organization in a variety of processes. The encoded unbound receptor for OGF has been localized to the outer nuclear envelope, where it binds OGF and is translocated into the nucleus. The coding sequence of this gene contains a polymorphic region of 60 nt tandem imperfect repeat units. Several transcripts containing between zero and eight repeat units have been reported.

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