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The antibody against OGFR was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human OGFR (NP_031372.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.
The antibody against OGFR was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human OGFR (NP_031372.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.
| Cat.No | ADA-11055A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | OGFR |
| Target Synonyms | OGFR | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.05% proclin300, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat brain, A-549, HepG2, Mouse brain, Mouse lung | Application | ELISA, WB, IF/ICC, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human OGFR (NP_031372.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9NZT2 | Immunogen Sequence |
Uniprot Id
Q9NZT2
Target Species
Human
Target Name
OGFR
Target Full Name
Opioid growth factor receptor
Target Function
Receptor for opioid growth factor (OGF), also known as Met-enkephalin. Seems to be involved in growth regulation.
Target Subcellular Location
Cytoplasm. Nucleus. Note=The OGF/OGFR complex is probably translocated to the nucleus.
Target Protein Families
Opioid growth factor receptor family
Target Tissue Specificity
Highly expressed in the heart and liver, moderately in skeletal muscle and kidney and to a lesser extent in brain and pancreas. Expressed in fetal tissues including liver and kidney.
Target Research Area
Cell Biology
Target Synonyms
7 60 protein; HGNC:15768; Met enkephalin receptor; OGFr; OGFR_HUMAN; Opioid growth factor receptor; Protein 7-60; Zeta Opioid Receptor; Zeta type opioid receptor; Zeta-type opioid receptor
Target Background
The protein encoded by this gene is a receptor for opioid growth factor (OGF), also known as [Met(5)]-enkephalin. OGF is a negative regulator of cell proliferation and tissue organization in a variety of processes. The encoded unbound receptor for OGF has been localized to the outer nuclear envelope, where it binds OGF and is translocated into the nucleus. The coding sequence of this gene contains a polymorphic region of 60 nt tandem imperfect repeat units. Several transcripts containing between zero and eight repeat units have been reported.
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