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Rabbit anti-Human OGFR Polyclonal Antibody

The antibody against OGFR was raised in rabbit using the Human OGFR as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

ADC-47745A

The antibody against OGFR was raised in rabbit using the Human OGFR as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

$600.00

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Specifications


Cat.No ADC-47745A ClonalityPolyclonal
Host SpeciesRabbitTarget NameOGFR
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman OGFRTarget SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9NZT2
Background Information
  • Uniprot Id

    Q9NZT2

  • Target Species

    Human

  • Target Name

    OGFR

  • Target Full Name

    Opioid growth factor receptor

  • Target Function

    Receptor for opioid growth factor (OGF), also known as Met-enkephalin. Seems to be involved in growth regulation.

  • Target Subcellular Location

    Cytoplasm. Nucleus. Note=The OGF/OGFR complex is probably translocated to the nucleus.

  • Target Protein Families

    Opioid growth factor receptor family

  • Target Tissue Specificity

    Highly expressed in the heart and liver, moderately in skeletal muscle and kidney and to a lesser extent in brain and pancreas. Expressed in fetal tissues including liver and kidney.

  • Target Research Area

    Cell Biology

  • Target Synonyms

    7 60 protein; HGNC:15768; Met enkephalin receptor; OGFr; OGFR_HUMAN; Opioid growth factor receptor; Protein 7-60; Zeta Opioid Receptor; Zeta type opioid receptor; Zeta-type opioid receptor

  • Target Background

    The protein encoded by this gene is a receptor for opioid growth factor (OGF), also known as [Met(5)]-enkephalin. OGF is a negative regulator of cell proliferation and tissue organization in a variety of processes. The encoded unbound receptor for OGF has been localized to the outer nuclear envelope, where it binds OGF and is translocated into the nucleus. The coding sequence of this gene contains a polymorphic region of 60 nt tandem imperfect repeat units. Several transcripts containing between zero and eight repeat units have been reported.

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