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Rabbit anti-Human OGN Polyclonal Antibody

The antibody against OGN was raised in rabbit using the Recombinant Human Mimecan protein (20-298AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

ADC-17386A

The antibody against OGN was raised in rabbit using the Recombinant Human Mimecan protein (20-298AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

$299.00

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Specifications


Cat.No ADC-17386A ClonalityPolyclonal
Host SpeciesRabbitTarget NameOGN
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Mimecan protein (20-298AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP20774
Background Information
  • Uniprot Id

    P20774

  • Target Species

    Human

  • Target Name

    OGN

  • Target Full Name

    Mimecan

  • Target Function

    Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2.

  • Target Subcellular Location

    Secreted, extracellular space, extracellular matrix.

  • Target Protein Families

    Small leucine-rich proteoglycan (SLRP) family, SLRP class III subfamily

  • Target Tissue Specificity

    Bone.

  • Target Research Area

    Signal Transduction

  • Target Synonyms

    Corneal keratan sulfate proteoglycan; DKFZP586P2421; MIME_HUMAN; Mimecan; Mimecan proteoglycan; OG; OGN; OIF; Osteoglycin; Osteoinductive factor; SLRR3A

  • Target Background

    This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. The encoded protein induces ectopic bone formation in conjunction with transforming growth factor beta and may regulate osteoblast differentiation. High expression of the encoded protein may be associated with elevated heart left ventricular mass. Alternative splicing results in multiple transcript variants.

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