Rabbit anti-Human OLA1 Polyclonal Antibody

The antibody against OLA1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 130-310 of human OLA1 (NP_037473.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.

ADA-09212A

Number

Cat.No	ADA-09212A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	OLA1
Target Synonyms	DOC45; GBP45; GTBP9; GTPBP9; PTD004; OLA1	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	Jurkat, MCF7, Mouse brain, Mouse lung, Rat testis, U-251MG	Application	ELISA, WB, IF/ICC, IHC-P

Cat.No

ADA-09212A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

OLA1

Target Synonyms

DOC45; GBP45; GTBP9; GTPBP9; PTD004; OLA1

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

Jurkat, MCF7, Mouse brain, Mouse lung, Rat testis, U-251MG

Application

ELISA, WB, IF/ICC, IHC-P

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 130-310 of human OLA1 (NP_037473.3).	Target Species	Human
Immunogen Sequence	DDITHVEGSVDPIRDIEIIHEELQLKDEEMIGPIIDKLEKVAVRGGDKKLKPEYDIMCKVKSWVIDQKKPVRFYHDWNDKEIEVLNKHLFLTSKPMVYLVNLSEKDYIRKKNKWLIKIKEWVDKYDPGALVIPFSGALELKLQELSAEERQKYLEANMTQSALPKIIKAGFAALQLEYFFT	Uniprot ID	Q9NTK5

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 130-310 of human OLA1 (NP_037473.3).

Target Species

Human

Immunogen Sequence

DDITHVEGSVDPIRDIEIIHEELQLKDEEMIGPIIDKLEKVAVRGGDKKLKPEYDIMCKVKSWVIDQKKPVRFYHDWNDKEIEVLNKHLFLTSKPMVYLVNLSEKDYIRKKNKWLIKIKEWVDKYDPGALVIPFSGALELKLQELSAEERQKYLEANMTQSALPKIIKAGFAALQLEYFFT

Uniprot ID

Q9NTK5

Background Information

Uniprot Id

Q9NTK5
Target Species

Human
Target Name

OLA1
Target Full Name

Obg-like ATPase 1
Target Function

Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.
Target Subcellular Location

Cytoplasm. Nucleus. Nucleus, nucleolus.
Target Protein Families

TRAFAC class OBG-HflX-like GTPase superfamily, OBG GTPase family, YchF/OLA1 subfamily
Target Tissue Specificity

Expressed in all tissues tested but its expression is more abundant in testis, liver, lung, and brain. Overexpressed in several malignancies, including cancers of the colon, rectum, ovary, lung, stomach, and uterus.
Target Research Area

Signal Transduction
Target Synonyms

DKFZp313H1942; DNA damage-regulated overexpressed in cancer 45 protein; DOC45; EC 3.6.3; GBP45; GTP-binding protein 9 (putative); GTP-binding protein 9; GTP-binding protein PTD004; homologous yeast-44.2 protein; Obg like ATPase 1; Obg-like ATPase 1; OLA1; OLA1_HUMAN; PTD004
Target Background

This gene encodes a member of the GTPase protein family. The encoded protein interacts with breast cancer-associated gene 1 (BRCA1) and BRCA1-associated RING domain protein (BARD1), and is involved in centrosome regulation. Overexpression of this gene has been observed in multiple types of cancer and may be associated with poor survival. Pseudogenes of this gene have been defined on chromosomes 17 and 22.

Rabbit anti-Human OLA1 Polyclonal Antibody

Specifications

Immunogen Information

Inquire Rabbit anti-Human OLA1 Polyclonal Antibody Now

Related Products