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Rabbit anti-Human OLFM1 Polyclonal Antibody

The antibody against OLFM1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 90-220 of human OLFM1 (NP_055094.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-08649A

The antibody against OLFM1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 90-220 of human OLFM1 (NP_055094.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-08649A ClonalityPolyclonal
Host SpeciesRabbitTarget NameOLFM1
Target SynonymsAMY; NOE1; OlfA; NOELIN1; OLFM1FormLiquid
Species ReactivityHuman, MouseIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesA-549, MCF7, Mouse brain, SW480ApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 90-220 of human OLFM1 (NP_055094.1).Target SpeciesHuman
Immunogen SequenceIEVLDRRTQRDLQYVEKMENQMKGLESKFKQVEESHKQHLARQFKAIKAKMDELRPLIPVLEEYKADAKLVLQFKEEVQNLTSVLNELQEEIGAYDYDELQSRVSNLEERLRACMQKLACGKLTGISDPVTUniprot IDQ99784
Background Information
  • Uniprot Id

    Q99784

  • Target Species

    Human

  • Target Name

    OLFM1

  • Target Full Name

    Noelin

  • Target Function

    Contributes to the regulation of axonal growth in the embryonic and adult central nervous system by inhibiting interactions between RTN4R and LINGO1. Inhibits RTN4R-mediated axon growth cone collapse. May play an important role in regulating the production of neural crest cells by the neural tube. May be required for normal responses to olfactory stimuli.

  • Target Subcellular Location

    Secreted. Cell junction, synapse. Endoplasmic reticulum. Cell projection, axon. Perikaryon.

  • Target Synonyms

    AMY; NEUROBLASTOMA PROTEIN; Neuronal olfactomedin-related ER localized protein; Noe1; NOE1_HUMAN; Noel; Noel1; Noelin; Noelin1; OlfA; Olfactomedin 1; Olfactomedin-1; Olfm1; Pancortin 1; Pancortin

  • Target Background

    This gene product shares extensive sequence similarity with the rat neuronal olfactomedin-related ER localized protein. While the exact function of the encoded protein is not known, its abundant expression in brain suggests that it may have an essential role in nerve tissue. Several alternatively spliced transcripts encoding different isoforms have been found for this gene.

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