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Rabbit anti-Human OPA3 Polyclonal Antibody

The antibody against OPA3 was raised in rabbit using the Recombinant Human Optic atrophy 3 protein (25-179AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC, IF.

ADC-16836A

The antibody against OPA3 was raised in rabbit using the Recombinant Human Optic atrophy 3 protein (25-179AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC, IF.

$299.00

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Specifications


Cat.No ADC-16836A ClonalityPolyclonal
Host SpeciesRabbitTarget NameOPA3
Target SynonymsOPA3 antibody; Optic atrophy 3 protein antibodyFormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA, IF, IHC
StorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Optic atrophy 3 protein (25-179AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9H6K4
Background Information
  • Uniprot Id

    Q9H6K4

  • Target Species

    Human

  • Target Name

    OPA3

  • Target Full Name

    Optic atrophy 3 protein

  • Target Function

    May play some role in mitochondrial processes.

  • Target Involvement

    3-methylglutaconic aciduria 3 (MGA3); Optic atrophy 3 (OPA3)

  • Target Subcellular Location

    Mitochondrion.

  • Target Protein Families

    OPA3 family

  • Target Tissue Specificity

    Ubiquitous. Most prominent expression in skeletal muscle and kidney.

  • Target Synonyms

    OPA3; Optic atrophy 3 protein

  • Target Background

    The mouse ortholog of this protein co-purifies with the mitochondrial inner membrane. Mutations in this gene have been shown to result in 3-methylglutaconic aciduria type III and autosomal dominant optic atrophy and cataract. Multiple transcript variants encoding different isoforms have been found for this gene.

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