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Rabbit anti-Human OPLAH Polyclonal Antibody

The antibody against OPLAH was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1119-1288 of human OPLAH (NP_060040.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-09245A

The antibody against OPLAH was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1119-1288 of human OPLAH (NP_060040.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-09245A ClonalityPolyclonal
Host SpeciesRabbitTarget NameOPLAH
Target SynonymsOPLA; OPLAHD; 5-Opase; OPLAHFormLiquid
Species ReactivityHuman, MouseIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse kidney, K-562, Mouse brain, Mouse liverApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 1119-1288 of human OPLAH (NP_060040.1).Target SpeciesHuman
Immunogen SequenceTVAGGAGAGPSWHGRSGVHSHMTNTRITDPEILESRYPVILRRFELRRGSGGRGRFRGGDGVTRELLFREEALLSVLTERRAFRPYGLHGGEPGARGLNLLIRKNGRTVNLGGKTSVTVYPGDVFCLHTPGGGGYGDPEDPAPPPGSPPQALAFPEHGSVYEYRRAQEAVUniprot IDO14841
Background Information
  • Uniprot Id

    O14841

  • Target Species

    Human

  • Target Name

    OPLAH

  • Target Full Name

    5-oxoprolinase

  • Target Function

    Catalyzes the cleavage of 5-oxo-L-proline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.

  • Target Involvement

    5-oxoprolinase deficiency (OPLAHD)

  • Target Protein Families

    Oxoprolinase family

  • Target Research Area

    Metabolism

  • Target Synonyms

    5 Opase; 5 oxo L prolinase; 5 oxoprolinase (ATP hydrolysing); 5 oxoprolinase; 5-OPase; 5-oxo-L-prolinase; 5-oxoprolinase; DKFZp434H244; OPLA; OPLA_HUMAN; oplah; OPLAHD; Pyroglutamase

  • Target Background

    The protein encoded by this gene acts as a homodimer, using ATP hydrolysis to catalyze the conversion of 5-oxo-L-proline to L-glutamate. Defects in this gene are a cause of 5-oxoprolinase deficiency (OPLAHD).

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