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The antibody against Osteoglycin (OGN) was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 20-298 of human Osteoglycin (OGN) (NP_054776.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.
The antibody against Osteoglycin (OGN) was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 20-298 of human Osteoglycin (OGN) (NP_054776.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.
| Cat.No | ADA-02892A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | Osteoglycin (OGN) |
| Target Synonyms | OG; OIF; SLRR3A; Osteoglycin (OGN) | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | C2C12, Mouse lung | Application | ELISA, WB, IF/ICC, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 20-298 of human Osteoglycin (OGN) (NP_054776.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P20774 | Immunogen Sequence |
Uniprot Id
P20774
Target Species
Human
Target Name
OGN
Target Full Name
Mimecan
Target Function
Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2.
Target Subcellular Location
Secreted, extracellular space, extracellular matrix.
Target Protein Families
Small leucine-rich proteoglycan (SLRP) family, SLRP class III subfamily
Target Tissue Specificity
Bone.
Target Research Area
Signal Transduction
Target Synonyms
Corneal keratan sulfate proteoglycan; DKFZP586P2421; MIME_HUMAN; Mimecan; Mimecan proteoglycan; OG; OGN; OIF; Osteoglycin; Osteoinductive factor; SLRR3A
Target Background
This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. The encoded protein induces ectopic bone formation in conjunction with transforming growth factor beta and may regulate osteoblast differentiation. High expression of the encoded protein may be associated with elevated heart left ventricular mass. Alternative splicing results in multiple transcript variants.
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