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Rabbit anti-Human OSTF1 Polyclonal Antibody

The antibody against OSTF1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 15-214 of human OSTF1 (NP_036515.4) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-02217A

The antibody against OSTF1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 15-214 of human OSTF1 (NP_036515.4) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-02217A ClonalityPolyclonal
Host SpeciesRabbitTarget NameOSTF1
Target SynonymsOSF; SH3P2; bA235O14.1; OSTF1FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesHeLa, 293T, B cells, HepG2, Mouse brain, Rat kidneyApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 15-214 of human OSTF1 (NP_036515.4).Target SpeciesHuman
Immunogen SequenceKVFRALYTFEPRTPDELYFEEGDIIYITDMSDTNWWKGTSKGRTGLIPSNYVAEQAESIDNPLHEAAKRGNLSWLRECLDNRVGVNGLDKAGSTALYWACHGGHKDIVEMLFTQPNIELNQQNKLGDTALHAAAWKGYADIVQLLLAKGARTDLRNIEKKLAFDMATNAACASLLKKKQGTDAVRTLSNAEDYLDDEDSDUniprot IDQ92882
Background Information
  • Uniprot Id

    Q92882

  • Target Species

    Human

  • Target Name

    OSTF1

  • Target Full Name

    Osteoclast-stimulating factor 1

  • Target Function

    Induces bone resorption, acting probably through a signaling cascade which results in the secretion of factor(s) enhancing osteoclast formation and activity.

  • Target Subcellular Location

    Cytoplasm.

  • Target Tissue Specificity

    Ubiquitously expressed. Present in osteoclasts (at protein level).

  • Target Synonyms

    bA235O14.1; FLJ20559; OSF; Osteoclast stimulating factor 1; Osteoclast-stimulating factor 1; Ostf1; OSTF1_HUMAN; SH3P2

  • Target Background

    Osteoclast-stimulating factor-1 is an intracellular protein produced by osteoclasts that indirectly induces osteoclast formation and bone resorption (Reddy et al., 1998 [PubMed 10092216]).

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