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The antibody against PAIP2 was raised in rabbit using the Recombinant Human Polyadenylate-binding protein-interacting protein 2 protein (1-127AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against PAIP2 was raised in rabbit using the Recombinant Human Polyadenylate-binding protein-interacting protein 2 protein (1-127AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
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Immunohistochemistry of paraffin-embedded human lung tissue using PAIP2 Antibody at dilution of 1:1002
| Cat.No | ADC-18499A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PAIP2 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Polyadenylate-binding protein-interacting protein 2 protein (1-127AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9BPZ3 |
Uniprot Id
Q9BPZ3
Target Species
Human
Target Name
PAIP2
Target Full Name
Polyadenylate-binding protein-interacting protein 2
Target Function
Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization.
Target Subcellular Location
Cytoplasm.
Target Protein Families
PAIP2 family
Target Tissue Specificity
Expressed at highest level in testis, but also abundant in brain, cervix, lung, ovary, placenta, adipose tissue, thymus and thyroid.
Target Research Area
Epigenetics and Nuclear Signaling
Target Synonyms
PABP-interacting protein 2; PAIP-2; PAIP2; PAIP2_HUMAN; poly(A) binding protein interacting protein 2; Poly(A)-binding protein-interacting protein 2; Polyadenylate-binding protein-interacting protein 2
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