Rabbit anti-Human Pannexin 1 Polyclonal Antibody

The antibody against Pannexin 1 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 50-150 of human Pannexin 1 (NP_056183.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-11086A

Number

Cat.No	ADA-11086A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	Pannexin 1
Target Synonyms	PX1; MRS1; OOMD7; OZEMA7; UNQ2529; Pannexin 1	Form	Liquid
Species Reactivity	Human, Mouse	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	HeLa, DU145, MCF7, Mouse brain, Mouse skin, Mouse spleen	Application	ELISA, WB

Cat.No

ADA-11086A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

Pannexin 1

Target Synonyms

PX1; MRS1; OOMD7; OZEMA7; UNQ2529; Pannexin 1

Form

Liquid

Species Reactivity

Human, Mouse

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

HeLa, DU145, MCF7, Mouse brain, Mouse skin, Mouse spleen

Application

ELISA, WB

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 50-150 of human Pannexin 1 (NP_056183.2).	Target Species	Human
Immunogen Sequence	ISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVY	Uniprot ID	Q96RD7

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 50-150 of human Pannexin 1 (NP_056183.2).

Target Species

Human

Immunogen Sequence

ISLAFAQEISIGTQISCFSPSSFSWRQAAFVDSYCWAAVQQKNSLQSESGNLPLWLHKFFPYILLLFAILLYLPPLFWRFAAAPHICSDLKFIMEELDKVY

Uniprot ID

Q96RD7

Background Information

Uniprot Id

Q96RD7
Target Species

Human
Target Name

PANX1
Target Full Name

Pannexin-1
Target Function

Structural component of the gap junctions and the hemichannels involved in the ATP release and nucleotide permeation. May play a role as a Ca(2+)-leak channel to regulate ER Ca(2+) homeostasis. Plays a critical role in oogenesis.
Target Subcellular Location

Cell membrane; Multi-pass membrane protein. Cell junction, gap junction. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Target Protein Families

Pannexin family
Target Tissue Specificity

Widely expressed. Highest expression is observed in oocytes and brain. Detected at very low levels in sperm cells.
Target Synonyms

PANX1; MRS1; UNQ2529/PRO6028; Pannexin-1
Target Background

The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 2 are abundantly expressed in central nerve system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 2 may form cell type-specific gap junctions with distinct properties.

Rabbit anti-Human Pannexin 1 Polyclonal Antibody

Specifications

Immunogen Information

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