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The antibody against PANX1 was raised in rabbit using the Recombinant Human Pannexin-1 protein (288-426AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against PANX1 was raised in rabbit using the Recombinant Human Pannexin-1 protein (288-426AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
$299.00
Immunohistochemistry of paraffin-embedded human small intestine tissue using PANX1 Antibody at dilution of 1:1002
| Cat.No | ADC-08164A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PANX1 |
| Target Synonyms | PANX1; MRS1; UNQ2529/PRO6028; Pannexin-1 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Pannexin-1 protein (288-426AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96RD7 |
Uniprot Id
Q96RD7
Target Species
Human
Target Name
PANX1
Target Full Name
Pannexin-1
Target Function
Structural component of the gap junctions and the hemichannels involved in the ATP release and nucleotide permeation. May play a role as a Ca(2+)-leak channel to regulate ER Ca(2+) homeostasis. Plays a critical role in oogenesis.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Target Protein Families
Pannexin family
Target Tissue Specificity
Widely expressed. Highest expression is observed in oocytes and brain. Detected at very low levels in sperm cells.
Target Synonyms
PANX1; MRS1; UNQ2529/PRO6028; Pannexin-1
Target Background
The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 2 are abundantly expressed in central nerve system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 2 may form cell type-specific gap junctions with distinct properties.
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