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Rabbit anti-Human PAPD4 Polyclonal Antibody

The antibody against PAPD4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PAPD4 (NP_776158.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-03543A

The antibody against PAPD4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PAPD4 (NP_776158.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-03543A ClonalityPolyclonal
Host SpeciesRabbitTarget NamePAPD4
Target SynonymsAPD4; GLD2; TUT2; PAPD4FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse heart, Rat heart, BxPC-3, U-87MGApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PAPD4 (NP_776158.2).Target SpeciesHuman
Uniprot IDQ6PIY7Immunogen Sequence
Background Information
  • Uniprot Id

    Q6PIY7

  • Target Species

    Human

  • Target Name

    TENT2

  • Target Full Name

    Poly(A) RNA polymerase GLD2

  • Target Function

    Cytoplasmic poly(A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific RNAs, forming a poly(A) tail. In contrast to the canonical nuclear poly(A) RNA polymerase, it only adds poly(A) to selected cytoplasmic mRNAs. Does not play a role in replication-dependent histone mRNA degradation. Adds a single nucleotide to the 3' end of specific miRNAs, monoadenylation stabilizes and prolongs the activity of some but not all miRNAs.

  • Target Subcellular Location

    Cytoplasm. Nucleus.

  • Target Protein Families

    DNA polymerase type-B-like family, GLD2 subfamily

  • Target Tissue Specificity

    Expressed in brain. Within brain, it is expressed in cerebellum, hippocampus and medulla.

  • Target Synonyms

    TENT2; GLD2; PAPD4Poly(A) RNA polymerase GLD2; hGLD-2; EC 2.7.7.19; PAP-associated domain-containing protein 4; Terminal nucleotidyltransferase 2; Terminal uridylyltransferase 2; TUTase 2

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