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The antibody against L1 was raised in rabbit using the Recombinant Human papillomavirus type 16 Major capsid protein L1 protein (6-471AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against L1 was raised in rabbit using the Recombinant Human papillomavirus type 16 Major capsid protein L1 protein (6-471AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-17617A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | L1 |
| Target Synonyms | L1 antibody; Major capsid protein L1 antibody | Form | Liquid |
| Species Reactivity | Human papillomavirus type 16 | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human papillomavirus type 16 Major capsid protein L1 protein (6-471AA) | Target Species | Human papillomavirus type 16 |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P03101 |
Uniprot Id
P03101
Target Species
Human papillomavirus type 16
Target Name
L1
Target Function
Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins. Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment. This binding mediates a conformational change in the virus capsid that facilitates efficient infection. The virion enters the host cell via endocytosis. During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus. The virion assembly takes place within the cell nucleus. Encapsulates the genomic DNA together with protein L2.
Target Subcellular Location
Virion. Host nucleus.
Target Protein Families
Papillomaviridae L1 protein family
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