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The antibody against PAPSS2 was raised in rabbit using the Recombinant Human Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 protein (2-138AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.
The antibody against PAPSS2 was raised in rabbit using the Recombinant Human Bifunctional 3′-phosphoadenosine 5′-phosphosulfate synthase 2 protein (2-138AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.
$299.00
| Cat.No | ADC-04924A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PAPSS2 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 protein (2-138AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O95340 |
Uniprot Id
O95340
Target Species
Human
Target Name
PAPSS2
Target Full Name
Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2
Target Function
Bifunctional enzyme with both ATP sulfurylase and APS kinase activity, which mediates two steps in the sulfate activation pathway. The first step is the transfer of a sulfate group to ATP to yield adenosine 5'-phosphosulfate (APS), and the second step is the transfer of a phosphate group from ATP to APS yielding 3'-phosphoadenylylsulfate/PAPS, the activated sulfate donor used by sulfotransferases. In mammals, PAPS is the sole source of sulfate while APS appears to only be an intermediate in the sulfate-activation pathway. Plays indirectly an important role in skeletogenesis during postnatal growth.
Target Involvement
Brachyolmia type 4 with mild epiphyseal and metaphyseal changes (BCYM4)
Target Protein Families
APS kinase family; Sulfate adenylyltransferase family
Target Tissue Specificity
Expressed in cartilage and adrenal gland.
Target Synonyms
PAPSS2; ATPSK2Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2; PAPS synthase 2; PAPSS 2; Sulfurylase kinase 2; SK 2; SK2) [Includes: Sulfate adenylyltransferase; EC 2.7.7.4; ATP-sulfurylase; Sulfate adenylate transferase; SAT); Adenylyl-sulfate kinase; EC 2.7.1.25; 3'-phosphoadenosine-5'-phosphosulfate synthase; APS kinase; Adenosine-5'-phosphosulfate 3'-phosphotransferase; Adenylylsulfate 3'-phosphotransferase)]
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