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The antibody against PARD3 was raised in rabbit using the Synthesized peptide derived from internal of Human PARD3. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB, IF.
The antibody against PARD3 was raised in rabbit using the Synthesized peptide derived from internal of Human PARD3. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB, IF.
$297.00
Western blot analysis of extracts from COLO205 cells, using PARD3 antibody.
Immunofluorescence analysis of HepG2 cells, using PARD3 antibody.2
| Cat.No | ADC-41870A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PARD3 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Application | ELISA, IF, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from internal of Human PARD3. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8TEW0 |
Uniprot Id
Q8TEW0
Target Species
Human
Target Name
PARD3
Target Full Name
Partitioning defective 3 homolog
Target Function
Adapter protein involved in asymmetrical cell division and cell polarization processes. Seems to play a central role in the formation of epithelial tight junctions. Targets the phosphatase PTEN to cell junctions. Involved in Schwann cell peripheral myelination. Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. Required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons.
Target Involvement
Neural tube defects (NTD)
Target Subcellular Location
Cytoplasm. Endomembrane system. Cell junction. Cell junction, tight junction. Cell junction, adherens junction. Cell membrane. Cytoplasm, cell cortex. Cytoplasm, cytoskeleton.
Target Protein Families
PAR3 family
Target Tissue Specificity
Widely expressed.
Target Synonyms
agouti signaling protein; ASIP; Atypical PKC isotype specific interacting protein; Atypical PKC isotype-specific-interacting protein; Baz; bazooka; Coagulation factor II receptor-like 2; CTCL tumor antigen se2-5; F2rl2; PAR-3; par-3 family cell polarity regulator alpha; par-3 family cell polarity regulator; PAR3 alpha ; par3; PAR3-alpha; PARD-3; Pard3; PARD3_HUMAN; PARD3A; Partitioning defective 3 homolog; Partitioning-defective 3 homolog; Partitioning-defective protein 3; C. elegans; homolog of; SE2-5L16; SE2-5LT1; SE2-5T2; Thrombin receptor-like 2
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