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The antibody against PASD1 was raised in rabbit using the Recombinant Human Circadian clock protein PASD1 protein (301-600AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against PASD1 was raised in rabbit using the Recombinant Human Circadian clock protein PASD1 protein (301-600AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
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| Cat.No | ADC-24157A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PASD1 |
| Target Synonyms | Cancer/testis antigen 63 antibody; CT63 antibody; OX-TES-1 antibody; PAS domain containing 1 antibody; PAS domain-containing protein 1 antibody; PASD1 antibody; PASD1_HUMAN antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Biotin conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Circadian clock protein PASD1 protein (301-600AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8IV76 |
Uniprot Id
Q8IV76
Target Species
Human
Target Name
PASD1
Target Full Name
Circadian clock protein PASD1
Target Function
Functions as a suppressor of the biological clock that drives the daily circadian rhythms of cells throughout the body. Acts as a nuclear repressor of the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock components. Inhibits circadian clock function in cancer cells, when overexpressed.
Target Subcellular Location
[Isoform 1]: Nucleus.; [Isoform 2]: Nucleus.
Target Tissue Specificity
Testis-specific. Expressed in a broad range of cancer cells, including melanoma, lung cancer, and breast cancer (at protein level). Testis-specific. Found in histologically normal tissues from patients with uterus, lung and small intestine cancers. Widesp
Target Synonyms
Cancer/testis antigen 63; CT63; OX-TES-1; PAS domain containing 1; PAS domain-containing protein 1; PASD1; PASD1_HUMAN
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