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Rabbit anti-Human PCDH11Y Polyclonal Antibody

The antibody against PCDH11Y was raised in rabbit using the Human PCDH11Y as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

ADC-52437A

The antibody against PCDH11Y was raised in rabbit using the Human PCDH11Y as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

$600.00

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Specifications


Cat.No ADC-52437A ClonalityPolyclonal
Host SpeciesRabbitTarget NamePCDH11Y
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman PCDH11YTarget SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9BZA8
Background Information
  • Uniprot Id

    Q9BZA8

  • Target Species

    Human

  • Target Name

    PCDH11Y

  • Target Full Name

    Protocadherin-11 Y-linked

  • Target Function

    Potential calcium-dependent cell-adhesion protein.

  • Target Involvement

    A chromosomal aberration involving PCDH11Y is a cause of multiple congenital abnormalities, including severe bilateral vesicoureteral reflux (VUR) with ureterovesical junction defects. Translocation t(Y;3)(p11;p12) with ROBO2.

  • Target Subcellular Location

    Cell membrane; Single-pass type I membrane protein.

  • Target Tissue Specificity

    Expressed strongly in fetal brain and brain (cortex, amygdala, thalamus, substantia nigra, hippocampus, caudate nucleus and corpus callosum). Expressed at low level in testis. Expressed in apoptosis-resistant cells.

  • Target Synonyms

    PCDH11Y; PCDH11; PCDH22; PCDHY; Protocadherin-11 Y-linked; Protocadherin-11; Protocadherin on the Y chromosome; PCDH-Y; Protocadherin prostate cancer; Protocadherin-PC; Protocadherin-22

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