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The antibody against PCIF1 was raised in rabbit using the Recombinant Human Phosphorylated CTD-interacting factor 1 protein (201-500AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against PCIF1 was raised in rabbit using the Recombinant Human Phosphorylated CTD-interacting factor 1 protein (201-500AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
$299.00
Immunohistochemistry of paraffin-embedded human small intestine tissue using PCIF1 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human skin tissue using PCIF1 Antibody at dilution of 1:1002
| Cat.No | ADC-24146A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PCIF1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Phosphorylated CTD-interacting factor 1 protein (201-500AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9H4Z3 |
Uniprot Id
Q9H4Z3
Target Species
Human
Target Name
PCIF1
Target Full Name
mRNA (2'-O-methyladenosine-N(6)-)-methyltransferase
Target Function
Cap-specific adenosine methyltransferase that catalyzes formation of N(6),2'-O-dimethyladenosine cap (m6A(m)) by methylating the adenosine at the second transcribed position of capped mRNAs. Recruited to the early elongation complex of RNA polymerase II (RNAPII) via interaction with POLR2A and mediates formation of m6A(m) co-transcriptionally.
Target Subcellular Location
Nucleus.
Target Tissue Specificity
Ubiquitous.
Target Synonyms
bA465L10.1; C20orf67; Pcif1; PCIF1_HUMAN; PDX1 C terminal inhibiting factor 1; Phosphorylated CTD interacting factor 1; Phosphorylated CTD-interacting factor 1
Target Background
Enables RNA polymerase II C-terminal domain phosphoserine binding activity; S-adenosyl-L-methionine binding activity; and mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity. Involved in mRNA methylation; negative regulation of translation; and positive regulation of translation. Located in intercellular bridge; microtubule cytoskeleton; and nucleoplasm.
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