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The antibody against PCYT1A was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human PCYT1A (NP_001299602.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against PCYT1A was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human PCYT1A (NP_001299602.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-04121A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PCYT1A |
| Target Synonyms | CT; CTA; CCTA; CTPCT; PCYT1; SMDCRD; CCTalpha; PCYT1A | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, HepG2, Mouse brain, Mouse testis | Application | ELISA, WB |
| Immunogen Description | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PCYT1A (NP_001299602.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | MDAQCSAKVNARKRRKEAPGPNGATEEDGVPSKVQRCAVGLRQPAPFSDEIEVDFSKPYVRVTMEEASRGTPCERPVRVYADGIFDLFHSGHARALMQAK | Uniprot ID | P49585 |
Uniprot Id
P49585
Target Species
Human
Target Name
PCYT1A
Target Full Name
Choline-phosphate cytidylyltransferase A
Target Function
Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis.
Target Involvement
Spondylometaphyseal dysplasia with cone-rod dystrophy (SMDCRD)
Target Subcellular Location
Cytoplasm, cytosol. Membrane; Peripheral membrane protein. Endoplasmic reticulum. Nucleus.
Target Protein Families
Cytidylyltransferase family
Target Tissue Specificity
Brain, placenta, liver, fetal and adult lung.
Target Synonyms
CCT A; CCT alpha ; CCT-alpha; Choline phosphate cytidylyltransferase A; Choline-phosphate cytidylyltransferase A; CT A; CT; CTP:phosphocholine cytidylyltransferase A; CTPCT; PCY1A_HUMAN; PCYT1; Pcyt1a; Phosphate cytidylyltransferase 1 choline alpha; Phosphate cytidylyltransferase 1 choline alpha isoform ; Phosphorylcholine transferase A
Target Background
This gene belongs to the cytidylyltransferase family and is involved in the regulation of phosphatidylcholine biosynthesis. Mutations in this gene are associated with spondylometaphyseal dysplasia with cone-rod dystrophy. Alternatively spliced transcript variants have been found for this gene.
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