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Rabbit anti-Human PCYT2 Polyclonal Antibody

The antibody against PCYT2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-389 of human PCYT2 (NP_002852.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-00603A

The antibody against PCYT2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-389 of human PCYT2 (NP_002852.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-00603A ClonalityPolyclonal
Host SpeciesRabbitTarget NamePCYT2
Target SynonymsET; SPG82; PCYT2FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive Samples293T, HepG2, MCF7, Mouse brain, Mouse liver, Rat liverApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 1-389 of human PCYT2 (NP_002852.1).Target SpeciesHuman
Uniprot IDQ99447Immunogen Sequence
Background Information
  • Uniprot Id

    Q99447

  • Target Species

    Human

  • Target Name

    PCYT2

  • Target Full Name

    Ethanolamine-phosphate cytidylyltransferase

  • Target Function

    Ethanolamine-phosphate cytidylyltransferase that catalyzes the second step in the synthesis of phosphatidylethanolamine (PE) from ethanolamine via the CDP-ethanolamine pathway. Phosphatidylethanolamine is a dominant inner-leaflet phospholipid in cell membranes, where it plays a role in membrane function by structurally stabilizing membrane-anchored proteins, and participates in important cellular processes such as cell division, cell fusion, blood coagulation, and apoptosis.

  • Target Protein Families

    Cytidylyltransferase family

  • Target Tissue Specificity

    Strongest expression in liver, heart, and skeletal muscle.

  • Target Synonyms

    CTP:phosphoethanolamine cytidylyltransferase; ET; Ethanolamine-phosphate cytidylyltransferase; Ethanolaminephosphate Cytidyltransferase; PCY2; PCY2_HUMAN; Pcyt2; Phosphate cytidylyltransferase 2 ethanolamine; Phosphorylethanolamine transferase

  • Target Background

    This gene encodes an enzyme that catalyzes the formation of CDP-ethanolamine from CTP and phosphoethanolamine in the Kennedy pathway of phospholipid synthesis. Alternative splicing results in multiple transcript variants.

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