Rabbit anti-Human PDCD1LG2 Polyclonal Antibody

The antibody against PDCD1LG2 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 100-200 of human PDCD1LG2 (NP_079515.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

ADA-06871A

Number

Cat.No	ADA-06871A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	PDCD1LG2
Target Synonyms	B7DC; Btdc; PDL2; CD273; PD-L2; PDCD1L2; bA574F11.2; PDCD1LG2	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.05% proclin300, pH7.3.	Purification Method	Affinity purification
Positive Samples	Rat spleen, Rat thymus	Application	ELISA, WB, IF/ICC

Cat.No

ADA-06871A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

PDCD1LG2

Target Synonyms

B7DC; Btdc; PDL2; CD273; PD-L2; PDCD1L2; bA574F11.2; PDCD1LG2

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.05% proclin300, pH7.3.

Purification Method

Affinity purification

Positive Samples

Rat spleen, Rat thymus

Application

ELISA, WB, IF/ICC

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 100-200 of human PDCD1LG2 (NP_079515.2).	Target Species	Human
Immunogen Sequence	YQCIIIYGVAWDYKYLTLKVKASYRKINTHILKVPETDEVELTCQATGYPLAEVSWPNVSVPANTSHSRTPEGLYQVTSVLRLKPPPGRNFSCVFWNTHVR	Uniprot ID	Q9BQ51

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 100-200 of human PDCD1LG2 (NP_079515.2).

Target Species

Human

Immunogen Sequence

YQCIIIYGVAWDYKYLTLKVKASYRKINTHILKVPETDEVELTCQATGYPLAEVSWPNVSVPANTSHSRTPEGLYQVTSVLRLKPPPGRNFSCVFWNTHVR

Uniprot ID

Q9BQ51

Background Information

Uniprot Id

Q9BQ51
Target Species

Human
Target Name

PDCD1LG2
Target Full Name

Programmed cell death 1 ligand 2
Target Function

Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
Target Subcellular Location

[Isoform 3]: Secreted.; [Isoform 2]: Endomembrane system; Single-pass type I membrane protein.; [Isoform 1]: Cell membrane; Single-pass type I membrane protein.
Target Protein Families

Immunoglobulin superfamily, BTN/MOG family
Target Tissue Specificity

Highly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus.
Target Research Area

Immunology
Target Synonyms

B7 dendritic cell molecule; B7-DC; B7DC; bA574F11.2; Btdc; Butyrophilin B7 DC; Butyrophilin B7-DC; Butyrophilin B7DC ; CD 273; CD273; CD273 antigen ; MGC142238; MGC142240; PD 1 ligand 2; PD L2; PD-1 ligand 2; PD-L2; PD1 ligand 2; PD1L2_HUMAN; PDCD 1 ligand 2; PDCD1 ligand 2; PDCD1L2; Pdcd1lg2; PDL 2; PDL2; Programmed cell death 1 ligand 2; Programmed death ligand 2
Target Background

Involved in negative regulation of activated T cell proliferation; negative regulation of interferon-gamma production; and negative regulation of interleukin-10 production. Predicted to be located in plasma membrane. Predicted to be active in external side of plasma membrane. Biomarker of pulmonary tuberculosis.

Rabbit anti-Human PDCD1LG2 Polyclonal Antibody

Specifications

Immunogen Information

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