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Rabbit anti-Human PDE6C Polyclonal Antibody

The antibody against PDE6C was raised in rabbit using the Recombinant Human Cone cGMP-specific 3\',5\'-cyclic phosphodiesterase subunit alpha\' protein (285-451AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IF.

ADC-04165A

The antibody against PDE6C was raised in rabbit using the Recombinant Human Cone cGMP-specific 3\’,5\’-cyclic phosphodiesterase subunit alpha\’ protein (285-451AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IF.

$299.00

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Specifications


Cat.No ADC-04165A ClonalityPolyclonal
Host SpeciesRabbitTarget NamePDE6C
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISA, IF, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' protein (285-451AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP51160
Background Information
  • Uniprot Id

    P51160

  • Target Species

    Human

  • Target Name

    PDE6C

  • Target Full Name

    Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'

  • Target Function

    As cone-specific cGMP phosphodiesterase, it plays an essential role in light detection and cone phototransduction by rapidly decreasing intracellular levels of cGMP.

  • Target Involvement

    Cone dystrophy 4 (COD4); Achromatopsia 5 (ACHM5)

  • Target Subcellular Location

    Cell membrane; Lipid-anchor; Cytoplasmic side.

  • Target Protein Families

    Cyclic nucleotide phosphodiesterase family

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