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The antibody against PDLIM3 was raised in rabbit using the Human PDLIM3 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against PDLIM3 was raised in rabbit using the Human PDLIM3 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$600.00
| Cat.No | ADC-52412A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PDLIM3 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Human PDLIM3 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q53GG5 |
Uniprot Id
Q53GG5
Target Species
Human
Target Name
PDLIM3
Target Full Name
PDZ and LIM domain protein 3
Target Function
May play a role in the organization of actin filament arrays within muscle cells.
Target Subcellular Location
Cytoplasm, myofibril, sarcomere, Z line. Note=Localizes to myofiber Z-lines.
Target Tissue Specificity
Isoform 1 is highly expressed in differentiated skeletal muscle. Isoform 2 is heart-specific.
Target Research Area
Signal Transduction
Target Synonyms
Actinin associated LIM protein; Actinin-associated LIM protein; Alpha actinin 2 associated LIM protein; Alpha-actinin-2-associated LIM protein; DKFZp686L0362; Enigma homolog; PDLI3_HUMAN; PDLIM 3; PDLIM3; PDZ and LIM domain 3; PDZ and LIM domain protein 3
Target Background
The protein encoded by this gene contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. In support of this, the encoded protein has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Aberrant alternative splicing of this gene may play a role in myotonic dystrophy.
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