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The antibody against PDS5A was raised in rabbit using the Recombinant Human Sister chromatid cohesion protein PDS5 homolog A protein (2-134AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against PDS5A was raised in rabbit using the Recombinant Human Sister chromatid cohesion protein PDS5 homolog A protein (2-134AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
Immunohistochemistry of paraffin-embedded human colon cancer using PDS5A Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human ovarian cancer using PDS5A Antibody at dilution of 1:1002
Immunofluorescent analysis of Hela cells using PDS5A Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)3
| Cat.No | ADC-13333A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PDS5A |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Sister chromatid cohesion protein PDS5 homolog A protein (2-134AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q29RF7 |
Uniprot Id
Q29RF7
Target Species
Human
Target Name
PDS5A
Target Full Name
Sister chromatid cohesion protein PDS5 homolog A
Target Function
Probable regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin. May couple sister chromatid cohesion during mitosis to DNA replication. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair.
Target Subcellular Location
Nucleus.
Target Protein Families
PDS5 family
Target Tissue Specificity
Highest level in colon. Low levels in lung, ovary, breast and kidney. Reduced level in renal tumor tissue. Isoform 2 is expressed in kidney.
Target Synonyms
Cell proliferation inducing protein 54 ; Cell proliferation-inducing gene 54 protein; KIAA0648; PDS5; regulator of cohesion maintenance; homolog A (S. cerevisiae); PDS5A; PDS5A_HUMAN; PIG54; SCC-112; SCC112; Sister chromatid cohesion protein 112; Sister chromatid cohesion protein PDS5 homolog A
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