Rabbit anti-Human PE Monoclonal Antibody

The antibody against PE was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 100-200 of human CD20 mAb (NP_068769.2) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on FC.

ADA-08278A

Number

Cat.No	ADA-08278A	Clonality	Monoclonal
Host Species	Rabbit	Target Name	PE
Target Synonyms	MS4A1; B1; Bp35; CD20; CVID5; LEU-16; MS4A2; S7; B-lymphocyte antigen CD20	Form	Liquid
Species Reactivity	Human	Isotype	IgG
Storage Buffer	0.2% BSA, PBS with 0.03% proclin300, pH7.3.	Purification Method	Affinity purification
Application	FC

Cat.No

ADA-08278A

Clonality

Monoclonal

Host Species

Rabbit

Target Name

Target Synonyms

MS4A1; B1; Bp35; CD20; CVID5; LEU-16; MS4A2; S7; B-lymphocyte antigen CD20

Form

Liquid

Species Reactivity

Human

Isotype

IgG

Storage Buffer

0.2% BSA, PBS with 0.03% proclin300, pH7.3.

Purification Method

Affinity purification

Application

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 100-200 of human CD20 mAb (NP_068769.2).	Target Species	Human
Immunogen Sequence	LLAATEKNSRKCLVKGKMIMNSLSLFAAISGMILSIMDILNIKISHFLKMESLNFIRAHTPYINIYNCEPANPSEKNSPSTQYCYSIQSLFLGILSVMLIF	Uniprot ID	P11836

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 100-200 of human CD20 mAb (NP_068769.2).

Target Species

Human

Immunogen Sequence

LLAATEKNSRKCLVKGKMIMNSLSLFAAISGMILSIMDILNIKISHFLKMESLNFIRAHTPYINIYNCEPANPSEKNSPSTQYCYSIQSLFLGILSVMLIF

Uniprot ID

P11836

Background Information

Uniprot Id

P11836
Target Species

Human
Target Name

MS4A1
Target Full Name

B-lymphocyte antigen CD20
Target Function

B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes. Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR.
Target Involvement

Immunodeficiency, common variable, 5 (CVID5)
Target Subcellular Location

Cell membrane; Multi-pass membrane protein. Cell membrane; Lipid-anchor.
Target Protein Families

MS4A family
Target Tissue Specificity

Expressed on B-cells.
Target Research Area

Immunology, Cancer
Target Synonyms

MS4A1; CD20; B-lymphocyte antigen CD20; B-lymphocyte surface antigen B1; Bp35; Leukocyte surface antigen Leu-16; Membrane-spanning 4-domains subfamily A member 1; CD antigen CD20
Target Background

This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein.

Rabbit anti-Human PE Monoclonal Antibody

Specifications

Immunogen Information

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