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The antibody against Pea3 / ETV4 was raised in Rabbit using the recombinant Protein corresponding to a sequence within amino acids 1-284 of human ETV4 (NP_001977.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.
The antibody against Pea3 / ETV4 was raised in Rabbit using the recombinant Protein corresponding to a sequence within amino acids 1-284 of human ETV4 (NP_001977.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.
| Cat.No | ADA-12129A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | Pea3 / ETV4 |
| Target Synonyms | E1AF; PEA3; E1A-F; PEAS3; Pea3 / ETV4 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.05% proclin300, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, Mouse heart, Rat heart, Mouse stomach, SW480 | Application | ELISA, WB, IF/ICC, IHC-P |
| Immunogen Description | Recombinant Protein corresponding to a sequence within amino acids 1-284 of human ETV4 (NP_001977.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P43268 | Immunogen Sequence |
Uniprot Id
P43268
Target Species
Human
Target Name
ETV4
Target Full Name
ETS translocation variant 4
Target Function
Transcriptional activator. May play a role in keratinocyte differentiation.; (Microbial infection) Binds to the enhancer of the adenovirus E1A gene and acts as a transcriptional activator; the core-binding sequence is 5'-[AC]GGA[AT]GT-3'.
Target Subcellular Location
Nucleus.
Target Protein Families
ETS family
Target Tissue Specificity
Expressed in keratinocytes.
Target Synonyms
Adenovirus E1A enhancer binding protein; Adenovirus E1A enhancer-binding protein; E1A F; E1A-F; ETS translocation variant 4; ets variant gene 4 (E1A enhancer binding protein E1AF); ETV4; ETV4_HUMAN; PEA3; PEA3 protein; PEAS3; Polyomavirus enhancer activator 3; Polyomavirus enhancer activator 3 homolog; Protein PEA3
Target Background
Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of keratinocyte differentiation and positive regulation of transcription by RNA polymerase II. Located in chromosome and nucleolus.
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