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The antibody against PEX14 was raised in rabbit using the Synthesized peptide derived from internal of Human PEX14. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB, IHC.
The antibody against PEX14 was raised in rabbit using the Synthesized peptide derived from internal of Human PEX14. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB, IHC.
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Western blot analysis of extracts from A549 cells, using PEX14 antibody.
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using PEX14 antibody.2
| Cat.No | ADC-41050A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PEX14 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from internal of Human PEX14. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O75381 |
Uniprot Id
O75381
Target Species
Human
Target Name
PEX14
Target Full Name
Peroxisomal membrane protein PEX14
Target Function
Peroxisome membrane protein that is an essential component of the peroxisomal import machinery. Functions as a docking factor for the predominantly cytoplasmic PTS1 receptor (PEX5). Plays a key role for peroxisome movement through a direct interaction with tubulin.
Target Involvement
Peroxisome biogenesis disorder complementation group K (PBD-CGK); Peroxisome biogenesis disorder 13A (PBD13A)
Target Subcellular Location
Peroxisome membrane; Peripheral membrane protein; Cytoplasmic side.
Target Protein Families
Peroxin-14 family
Target Synonyms
dJ734G22.2; NAPP2 ; NF E2 associated polypeptide 2 ; Peroxin 14 ; Peroxin-14; Peroxisomal biogenesis factor 14; Peroxisomal membrane anchor protein PEX14; Peroxisomal membrane anchor protein Pex14p; Peroxisomal membrane protein PEX14; pex14; PEX14_HUMAN; Pex14p; PTS1 receptor docking protein; PTS1 receptor-docking protein
Target Background
This gene encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C-terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in this gene results in one form of Zellweger syndrome.
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