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The antibody against PF4 was raised in rabbit using the Synthetic peptide from Human protein at AA range: 51-100 as the immunogen. This antibody exists as a non-conjugated antibody. The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. This antibody has been validated on IHC, ELISA.
The antibody against PF4 was raised in rabbit using the Synthetic peptide from Human protein at AA range: 51-100 as the immunogen. This antibody exists as a non-conjugated antibody. The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. This antibody has been validated on IHC, ELISA.
$167.00
Immunohistochemical analysis of paraffin-embedded human-spleen, antibody was diluted at 1:200
| Cat.No | ADC-13032A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PF4 |
| Form | Liquid | Species Reactivity | Human, Rat |
| Storage Buffer | PH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol., PBS | Purification Method | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Synthetic peptide from Human protein at AA range: 51-100 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P02776 |
Uniprot Id
P02776
Target Species
Human
Target Name
PF4
Target Full Name
Platelet factor 4
Target Function
Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form.
Target Subcellular Location
Secreted.
Target Protein Families
Intercrine alpha (chemokine CxC) family
Target Synonyms
C-X-C motif chemokine 4; Chemokine (C X C motif) ligand 4; Chemokine (CXC motif) ligand 4; chemokine ligand 4; CXCL 4; CXCL4; Iroplact; MGC138298; Oncostatin A; Oncostatin-A; OncostatinA; PF 4; PF-4; PF4; Pf4a; Platelet factor 4; PLF4_HUMAN; SCYB 4; SCYB4; short form; Small inducible cytokine subfamily B; Small inducible cytokine subfamily member 4
Target Background
This gene encodes a member of the CXC chemokine family. This chemokine is released from the alpha granules of activated platelets in the form of a homotetramer which has high affinity for heparin and is involved in platelet aggregation. This protein is chemotactic for numerous other cell type and also functions as an inhibitor of hematopoiesis, angiogenesis and T-cell function. The protein also exhibits antimicrobial activity against Plasmodium falciparum.
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