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The antibody against PFDN2 was raised in rabbit using the Recombinant Human Prefoldin subunit 2 protein (1-154AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against PFDN2 was raised in rabbit using the Recombinant Human Prefoldin subunit 2 protein (1-154AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
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Immunohistochemistry of paraffin-embedded human pancreatic tissue using PFDN2 Antibody at dilution of 1:1002
| Cat.No | ADC-22554A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PFDN2 |
| Target Synonyms | OTTHUMP00000029707 antibody; PFD2 antibody; PFD2_HUMAN antibody; PFDN2 antibody; prefoldin 2 antibody; Prefoldin subunit 2 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Prefoldin subunit 2 protein (1-154AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9UHV9 |
Uniprot Id
Q9UHV9
Target Species
Human
Target Name
PFDN2
Target Full Name
Prefoldin subunit 2
Target Function
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
Target Subcellular Location
Nucleus. Cytoplasm. Mitochondrion.
Target Protein Families
Prefoldin subunit beta family
Target Synonyms
OTTHUMP00000029707; PFD2; PFD2_HUMAN; PFDN2; prefoldin 2; Prefoldin subunit 2
Target Background
This gene encodes a member of the prefoldin beta subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils.
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