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The antibody against PGM1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PGM1 (NP_002624.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against PGM1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PGM1 (NP_002624.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-07756A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PGM1 |
| Target Synonyms | CDG1T; GSD14; PGM1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse heart, 293T, Hep G2, Mouse liver, Rat liver, U-251 MG | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PGM1 (NP_002624.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P36871 | Immunogen Sequence |
Uniprot Id
P36871
Target Species
Human
Target Name
PGM1
Target Full Name
Phosphoglucomutase-1
Target Function
This enzyme participates in both the breakdown and synthesis of glucose.
Target Involvement
Congenital disorder of glycosylation 1T (CDG1T)
Target Subcellular Location
[Isoform 1]: Cytoplasm.
Target Protein Families
Phosphohexose mutase family
Target Research Area
Metabolism
Target Synonyms
CDG1T; Glucose phosphomutase 1; GSD14; OTTHUMP00000010519; OTTHUMP00000010520; PGM 1; PGM1; PGM1_HUMAN; Phosphoglucomutase 1; Phosphoglucomutase-1; Phosphoglucomutase1
Target Background
The protein encoded by this gene is an isozyme of phosphoglucomutase (PGM) and belongs to the phosphohexose mutase family. There are several PGM isozymes, which are encoded by different genes and catalyze the transfer of phosphate between the 1 and 6 positions of glucose. In most cell types, this PGM isozyme is predominant, representing about 90% of total PGM activity. In red cells, PGM2 is a major isozyme. This gene is highly polymorphic. Mutations in this gene cause glycogen storage disease type 14. Alternativley spliced transcript variants encoding different isoforms have been identified in this gene.
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