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The antibody against PHC3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 100-300 of human PHC3 (NP_079223.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on IF/ICC, ELISA.
The antibody against PHC3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 100-300 of human PHC3 (NP_079223.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on IF/ICC, ELISA.
Immunofluorescence analysis of U2OS cells using PHC3 antibody. Blue: DAPI for nuclear staining.
| Cat.No | ADA-05819A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PHC3 |
| Target Synonyms | EDR3; HPH3; PHC3 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Application | ELISA, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 100-300 of human PHC3 (NP_079223.3). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q8NDX5 | Immunogen Sequence |
Uniprot Id
Q8NDX5
Target Species
Human
Target Name
PHC3
Target Full Name
Polyhomeotic-like protein 3
Target Function
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
Target Subcellular Location
Nucleus.
Target Synonyms
Early development regulator 3; Early development regulatory protein 3; EDR3; Homolog of polyhomeotic 3; HPH 3; hPH3; PH3; PHC 3 ; Phc3; PHC3_HUMAN; Polyhomeotic homolog 3 (Drosophila) ; Polyhomeotic homolog 3; Polyhomeotic-like protein 3
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