Rabbit anti-Human Phospho-Cdc6-S54 Monoclonal Antibody

The antibody against Phospho-Cdc6-S54 was raised in Rabbit using a synthetic phosphorylated peptide around S54 of human Cdc6 (Q99741) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-14207A

Number

Cat.No	ADA-14207A	Clonality	Monoclonal
Host Species	Rabbit	Target Name	Phospho-Cdc6-S54
Target Synonyms	CDC18L; HsCDC6; MGORS5; HsCDC18; Phospho-Cdc6-S54	Form	Liquid
Species Reactivity	Mouse	Isotype	IgG
Storage Buffer	50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	NIH/3T3 Hydroxyurea, NIH/3T3 Paclitaxel	Application	ELISA, WB

Cat.No

ADA-14207A

Clonality

Monoclonal

Host Species

Rabbit

Target Name

Phospho-Cdc6-S54

Target Synonyms

CDC18L; HsCDC6; MGORS5; HsCDC18; Phospho-Cdc6-S54

Form

Liquid

Species Reactivity

Mouse

Isotype

IgG

Storage Buffer

50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

NIH/3T3 Hydroxyurea, NIH/3T3 Paclitaxel

Application

ELISA, WB

Immunogen Description	A synthetic phosphorylated peptide around S54 of human Cdc6 (Q99741).	Target Species	Human
Immunogen Sequence	PLSPR	Uniprot ID	Q99741

Immunogen Description

A synthetic phosphorylated peptide around S54 of human Cdc6 (Q99741).

Target Species

Human

Immunogen Sequence

PLSPR

Uniprot ID

Q99741

Background Information

Uniprot Id

Q99741
Target Species

Human
Target Name

CDC6
Target Full Name

Cell division control protein 6 homolog
Target Function

Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated.
Target Involvement

Meier-Gorlin syndrome 5 (MGORS5)
Target Subcellular Location

Nucleus. Cytoplasm.
Target Protein Families

CDC6/cdc18 family
Target Synonyms

Cdc 18L; Cdc 6; CDC18 (cell division cycle 18; S.pombe; homolog) like; CDC18 (S.pombe); Cdc18 related protein; CDC18(S.pombe); Cdc18-related protein; Cdc18L; cdc6; CDC6 cell division cycle 6 homolog; CDC6 related protein; CDC6-related protein; CDC6_HUMAN; Cdc6p; CELL CYCLE CONTROLLER CDC6; Cell division control protein 6; Cell division control protein 6 homolog; Cell division cycle 6 homolog (S. cerevisiae); Cell division cycle 6 homolog; Cell division cycle 6; S. cerevisiae; homolog of; HsCDC 6; HsCDC18; HsCDC6; p62; p62(cdc 6); p62(cdc6)
Target Background

The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins.

Rabbit anti-Human Phospho-Cdc6-S54 Monoclonal Antibody

Specifications

Immunogen Information

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