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Rabbit anti-Human Phospho-JDP2 (T148) Polyclonal Antibody

The antibody against JDP2 was raised in rabbit using the Synthesized peptide derived from Human JDP2 around the phosphorylation site of T148. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on IHC, ELISA.

ADC-36416A

The antibody against JDP2 was raised in rabbit using the Synthesized peptide derived from Human JDP2 around the phosphorylation site of T148. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on IHC, ELISA.

$167.00

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Specifications


Cat.No ADC-36416A ClonalityPolyclonal
Host SpeciesRabbitTarget NameJDP2
Target SynonymsJdp2 antibody; JDP2_HUMAN antibody; Jun dimerization protein 2 antibody; JUNDM2 antibody; Progesterone receptor co-activator antibodyFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerolPurification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ConjugateNon-conjugatedApplicationELISA, IHC
StorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from Human JDP2 around the phosphorylation site of T148.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ8WYK2
Background Information
  • Uniprot Id

    Q8WYK2

  • Target Species

    Human

  • Target Name

    JDP2

  • Target Full Name

    Jun dimerization protein 2

  • Target Function

    Component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. Involved in a variety of transcriptional responses associated with AP-1 such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. Can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. May control transcription via direct regulation of the modification of histones and the assembly of chromatin.

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    BZIP family, ATF subfamily

  • Target Synonyms

    Jdp2; JDP2_HUMAN; Jun dimerization protein 2; JUNDM2; Progesterone receptor co-activator

  • Target Background

    Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and sequence-specific double-stranded DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Predicted to be part of chromatin. Predicted to be active in nucleus.

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