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Rabbit anti-Human Phospho-TOB1 (S164) Polyclonal Antibody

The antibody against TOB1 was raised in rabbit using the Synthesized peptide derived from Human TOB1 around the phosphorylation site of S164. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.

ADC-36686A

The antibody against TOB1 was raised in rabbit using the Synthesized peptide derived from Human TOB1 around the phosphorylation site of S164. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.

$167.00

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Specifications


Cat.No ADC-36686A ClonalityPolyclonal
Host SpeciesRabbitTarget NameTOB1
Target SynonymsTOB1 antibody; TOB antibody; TROB1 antibody; Protein Tob1 antibody; Transducer of erbB-2 1 antibodyFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerolPurification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ConjugateNon-conjugatedApplicationELISA, IHC, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from Human TOB1 around the phosphorylation site of S164.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP50616
Background Information
  • Uniprot Id

    P50616

  • Target Species

    Human

  • Target Name

    TOB1

  • Target Full Name

    Protein Tob1

  • Target Function

    Anti-proliferative protein; the function is mediated by association with deadenylase subunits of the CCR4-NOT complex. Mediates CPEB3-accelerated mRNA deadenylation by binding to CPEB3 and recruiting CNOT7 which leads to target mRNA deadenylation and decay.

  • Target Subcellular Location

    Cytoplasm. Nucleus.

  • Target Protein Families

    BTG family

  • Target Tissue Specificity

    Ubiquitous.

  • Target Synonyms

    TOB1; TOB; TROB1; Protein Tob1; Transducer of erbB-2 1

  • Target Background

    This gene encodes a member of the transducer of erbB-2 /B-cell translocation gene protein family. Members of this family are anti-proliferative factors that have the potential to regulate cell growth. The encoded protein may function as a tumor suppressor. Alternate splicing results in multiple transcript variants.

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