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The antibody against PIK3AP1 was raised in rabbit using the Recombinant Human Phosphoinositide 3-kinase adapter protein 1 protein (293-404AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.
The antibody against PIK3AP1 was raised in rabbit using the Recombinant Human Phosphoinositide 3-kinase adapter protein 1 protein (293-404AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.
$299.00
| Cat.No | ADC-06553A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PIK3AP1 |
| Target Synonyms | PIK3AP1 antibody; BCAPPhosphoinositide 3-kinase adapter protein 1 antibody; B-cell adapter for phosphoinositide 3-kinase antibody; B-cell phosphoinositide 3-kinase adapter protein 1 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Phosphoinositide 3-kinase adapter protein 1 protein (293-404AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q6ZUJ8 |
Uniprot Id
Q6ZUJ8
Target Species
Human
Target Name
PIK3AP1
Target Full Name
Phosphoinositide 3-kinase adapter protein 1
Target Function
Signaling adapter that contributes to B-cell development by linking B-cell receptor (BCR) signaling to the phosphoinositide 3-kinase (PI3K)-Akt signaling pathway. Has a complementary role to the BCR coreceptor CD19, coupling BCR and PI3K activation by providing a docking site for the PI3K subunit PIK3R1. Alternatively, links Toll-like receptor (TLR) signaling to PI3K activation, a process preventing excessive inflammatory cytokine production. Also involved in the activation of PI3K in natural killer cells. May be involved in the survival of mature B-cells via activation of REL.
Target Subcellular Location
Cytoplasm. Cell membrane; Peripheral membrane protein.
Target Tissue Specificity
Expressed in natural killer (NK) cells.
Target Synonyms
PIK3AP1; BCAPPhosphoinositide 3-kinase adapter protein 1; B-cell adapter for phosphoinositide 3-kinase; B-cell phosphoinositide 3-kinase adapter protein 1
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