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Rabbit anti-Human PIK3AP1 Polyclonal Antibody

The antibody against PIK3AP1 was raised in rabbit using the Recombinant Human Phosphoinositide 3-kinase adapter protein 1 protein (293-404AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.

ADC-06553A

The antibody against PIK3AP1 was raised in rabbit using the Recombinant Human Phosphoinositide 3-kinase adapter protein 1 protein (293-404AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.

$299.00

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Specifications


Cat.No ADC-06553A ClonalityPolyclonal
Host SpeciesRabbitTarget NamePIK3AP1
Target SynonymsPIK3AP1 antibody; BCAPPhosphoinositide 3-kinase adapter protein 1 antibody; B-cell adapter for phosphoinositide 3-kinase antibody; B-cell phosphoinositide 3-kinase adapter protein 1 antibodyFormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4Purification Method>95%, Protein G purified
ConjugateNon-conjugatedApplicationELISA, IF
StorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Phosphoinositide 3-kinase adapter protein 1 protein (293-404AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ6ZUJ8
Background Information
  • Uniprot Id

    Q6ZUJ8

  • Target Species

    Human

  • Target Name

    PIK3AP1

  • Target Full Name

    Phosphoinositide 3-kinase adapter protein 1

  • Target Function

    Signaling adapter that contributes to B-cell development by linking B-cell receptor (BCR) signaling to the phosphoinositide 3-kinase (PI3K)-Akt signaling pathway. Has a complementary role to the BCR coreceptor CD19, coupling BCR and PI3K activation by providing a docking site for the PI3K subunit PIK3R1. Alternatively, links Toll-like receptor (TLR) signaling to PI3K activation, a process preventing excessive inflammatory cytokine production. Also involved in the activation of PI3K in natural killer cells. May be involved in the survival of mature B-cells via activation of REL.

  • Target Subcellular Location

    Cytoplasm. Cell membrane; Peripheral membrane protein.

  • Target Tissue Specificity

    Expressed in natural killer (NK) cells.

  • Target Synonyms

    PIK3AP1; BCAPPhosphoinositide 3-kinase adapter protein 1; B-cell adapter for phosphoinositide 3-kinase; B-cell phosphoinositide 3-kinase adapter protein 1

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