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Rabbit anti-Human PIK3R4 Polyclonal Antibody

The antibody against PIK3R4 was raised in rabbit using the Human PIK3R4 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IF.

ADC-47627A

The antibody against PIK3R4 was raised in rabbit using the Human PIK3R4 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IF.

$600.00

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Specifications


Cat.No ADC-47627A ClonalityPolyclonal
Host SpeciesRabbitTarget NamePIK3R4
FormLiquidSpecies ReactivityHuman, Mouse, Rat
IsotypeIgGStorage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IF, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman PIK3R4Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ99570
Background Information
  • Uniprot Id

    Q99570

  • Target Species

    Human

  • Target Name

    PIK3R4

  • Target Full Name

    Phosphoinositide 3-kinase regulatory subunit 4

  • Target Function

    Regulatory subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and cytokinesis, probably in the context of PI3KC3-C2.

  • Target Subcellular Location

    Late endosome. Cytoplasmic vesicle, autophagosome. Membrane; Lipid-anchor.

  • Target Protein Families

    Protein kinase superfamily, Ser/Thr protein kinase family

  • Target Tissue Specificity

    Ubiquitously expressed.

  • Target Synonyms

    MGC102700; P150; Phosphatidylinositol 3 kinase associated p150; Phosphatidylinositol 3 kinase regulatory subunit polypeptide 4; Phosphatidylinositol 3 kinase regulatory subunit polypeptide 4 p150; Phosphoinositide 3 kinase adaptor protein; Phosphoinositide 3 kinase regulatory subunit 4; Phosphoinositide 3 kinase regulatory subunit 4 p150; Phosphoinositide 3 kinase regulatory subunit polypeptide 4; Phosphoinositide 3 kinase regulatory subunit polypeptide 4 p150; Phosphoinositide 3-kinase adaptor protein; Phosphoinositide 3-kinase regulatory subunit 4; PI3 kinase p150 subunit; PI3-kinase p150 subunit; PI3-kinase regulatory subunit 4; PI3R4_HUMAN; PIK3R 4; PIK3R4; VPS 15; VPS15

  • Target Background

    Predicted to enable protein serine/threonine kinase activity. Involved in positive regulation of phosphatidylinositol 3-kinase activity; receptor catabolic process; and regulation of cytokinesis. Located in late endosome and microtubule cytoskeleton.

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