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The antibody against PIR was raised in rabbit using the Human PIR as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against PIR was raised in rabbit using the Human PIR as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$600.00
| Cat.No | ADC-52354A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PIR |
| Target Synonyms | 3-dioxygenase PIR antibody; Iron binding nuclear protein antibody; Pir antibody; PIR_HUMAN antibody; Pirin antibody; Probable quercetin 2 antibody; probable quercetin 2, 3-dioxygenase PIR antibody; Probable quercetinase antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Human PIR | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O00625 |
Uniprot Id
O00625
Target Species
Human
Target Name
PIR
Target Full Name
Pirin
Target Function
Transcriptional coregulator of NF-kappa-B which facilitates binding of NF-kappa-B proteins to target kappa-B genes in a redox-state-dependent manner. May be required for efficient terminal myeloid maturation of hematopoietic cells. Has quercetin 2,3-dioxygenase activity (in vitro).
Target Subcellular Location
Nucleus. Cytoplasm.
Target Protein Families
Pirin family
Target Tissue Specificity
Highly expressed in a subset of melanomas. Detected at very low levels in most tissues (at protein level). Expressed in all tissues, with highest level of expression in heart and liver.
Target Synonyms
3-dioxygenase PIR; Iron binding nuclear protein; Pir; PIR_HUMAN; Pirin; Probable quercetin 2; probable quercetin 2,3-dioxygenase PIR; Probable quercetinase
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