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The antibody against PKD1L1 was raised in rabbit using the Recombinant Human Polycystic kidney disease protein 1-like 1 protein (921-1164AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against PKD1L1 was raised in rabbit using the Recombinant Human Polycystic kidney disease protein 1-like 1 protein (921-1164AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
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Immunohistochemistry of paraffin-embedded human liver tissue using PKD1L1 Antibody at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using PKD1L1 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)2
| Cat.No | ADC-09823A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PKD1L1 |
| Target Synonyms | PKD1L1 antibody; UNQ5785/PRO19563 antibody; Polycystic kidney disease protein 1-like 1 antibody; PC1-like 1 protein antibody; Polycystin-1L1 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Polycystic kidney disease protein 1-like 1 protein (921-1164AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8TDX9 |
Uniprot Id
Q8TDX9
Target Species
Human
Target Name
PKD1L1
Target Full Name
Polycystin-1-like protein 1
Target Function
Component of a ciliary calcium channel that controls calcium concentration within primary cilia without affecting cytoplasmic calcium concentration. Forms a heterodimer with PKD2L1 in primary cilia and forms a calcium-permeant ciliary channel that regulates sonic hedgehog/SHH signaling and GLI2 transcription. Does not constitute the pore-forming subunit. Also involved in left/right axis specification downstream of nodal flow: forms a complex with PKD2 in cilia to facilitate flow detection in left/right patterning.
Target Involvement
Heterotaxy, visceral, 8, autosomal (HTX8)
Target Subcellular Location
Cell projection, cilium membrane; Multi-pass membrane protein.
Target Protein Families
Polycystin family
Target Tissue Specificity
Detected in testis and in fetal and adult heart.
Target Synonyms
PKD1L1; UNQ5785/PRO19563; Polycystic kidney disease protein 1-like 1; PC1-like 1 protein; Polycystin-1L1
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