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The antibody against PKD1L2 was raised in rabbit using the Recombinant Human Polycystic kidney disease protein 1-like 2 protein (1-306AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC, IF.
The antibody against PKD1L2 was raised in rabbit using the Recombinant Human Polycystic kidney disease protein 1-like 2 protein (1-306AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC, IF.
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Immunohistochemistry of paraffin-embedded human placenta tissue using PKD1L2 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human breast cancer using PKD1L2 Antibody at dilution of 1:1002
Immunofluorescent analysis of MCF-7 cells using PKD1L2 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)3
| Cat.No | ADC-24070A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PKD1L2 |
| Target Synonyms | PKD1L2 antibody; KIAA1879 antibody; PC1L2 antibody; Polycystic kidney disease protein 1-like 2 antibody; PC1-like 2 protein antibody; Polycystin-1L2 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Polycystic kidney disease protein 1-like 2 protein (1-306AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q7Z442 |
Uniprot Id
Q7Z442
Target Species
Human
Target Name
PKD1L2
Target Full Name
Polycystin-1-like protein 2
Target Function
May function as an ion-channel regulator. May function as a G-protein-coupled receptor.
Target Subcellular Location
Membrane; Multi-pass membrane protein.
Target Protein Families
Polycystin family
Target Tissue Specificity
Expressed in all tissues tested including brain, placenta, mammary gland, testis, lung and liver. Highest expression in skeletal muscle. Isoform 2 is expressed in heart and kidney.
Target Synonyms
PKD1L2; KIAA1879; PC1L2; Polycystic kidney disease protein 1-like 2; PC1-like 2 protein; Polycystin-1L2
Target Background
This gene encodes a member of the polycystin protein family. This protein may function as a G-protein-coupled component or regulator of cation channel pores. The long isoform of this protein contains 11 transmembrane domains, a latrophilin/CL-1-like GPCR proteolytic site (GPS) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain. Alternative splicing results in multiple transcript variants encoding distinct isoforms. This gene is a polymorphic pseudogene in humans.
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