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Rabbit anti-Human PKP4 Polyclonal Antibody

The antibody against PKP4 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human Plakophilin 4. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.

ADC-34255A

The antibody against PKP4 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human Plakophilin 4. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.

$167.00

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Specifications


Cat.No ADC-34255A ClonalityPolyclonal
Host SpeciesRabbitTarget NamePKP4
FormLiquidSpecies ReactivityHuman, Mouse
IsotypeIgGStorage Buffer0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol
Purification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.ConjugateNon-conjugated
ApplicationELISA, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from the Internal region of Human Plakophilin 4.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ99569
Background Information
  • Uniprot Id

    Q99569

  • Target Species

    Human

  • Target Name

    PKP4

  • Target Full Name

    Plakophilin-4

  • Target Function

    Plays a role as a regulator of Rho activity during cytokinesis. May play a role in junctional plaques.

  • Target Subcellular Location

    Cell junction, desmosome. Cytoplasm, cytoskeleton, spindle. Midbody. Cell membrane; Peripheral membrane protein. Note=Associated with the pericentrosomal region in interphase and with spindle poles during mitosis. In anaphase, during chromosome segregation, is recruited to the central microtubule bundle, focussed at the spindle midzone and ultimately localizes to the midbody at cytokinesis. Constituent of the midbody cytoskeletal matrix. Colocalized with desmoplakin at desmosomal junctional plaques in cultured epithelial cells.

  • Target Protein Families

    Beta-catenin family

  • Target Synonyms

    Catenin 4; Catenin4; FLJ31261; FLJ42243; p0071; PKP 4; PKP4; PKP4_HUMAN; Plakophilin 4; Plakophilin-4; Plakophilin4

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