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The antibody against PLA1A was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human PLA1A. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.
The antibody against PLA1A was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human PLA1A. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.
$167.00
Western Blot analysis of 3T3 cells using PLA1A Polyclonal Antibody
| Cat.No | ADC-34762A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PLA1A |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the C-terminal region of Human PLA1A. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q53H76 |
Uniprot Id
Q53H76
Target Species
Human
Target Name
PLA1A
Target Full Name
Phospholipase A1 member A
Target Function
Hydrolyzes the ester bond of the acyl group attached at the sn-1 position of phosphatidylserines (phospholipase A1 activity) and 1-acyl-2-lysophosphatidylserines (lysophospholipase activity) in the pathway of phosphatidylserines acyl chain remodeling. Cleaves phosphatidylserines exposed on the outer leaflet of the plasma membrane of apoptotic cells producing 2-acyl-1-lysophosphatidylserines, which in turn enhance mast cell activation and histamine production. Has no activity toward other glycerophospholipids including phosphatidylcholines, phosphatidylethanolamines, phosphatidic acids or phosphatidylinositols, or glycerolipids such as triolein.; Hydrolyzes lyso-PS but not PS.
Target Subcellular Location
Secreted.
Target Protein Families
AB hydrolase superfamily, Lipase family
Target Tissue Specificity
Widely expressed. Expressed in placenta, prostate and liver. Weakly or not expressed in skin, leukocytes, platelets, colon, spleen, lung, muscle and kidney.
Target Synonyms
AA986889; NMD; OTTHUMP00000215248; OTTHUMP00000215249; OTTHUMP00000215250; Phosphatidylserine specific phospholipase A1; Phosphatidylserine specific phospholipase A1alpha; Phosphatidylserine-specific phospholipase A1; Phospholipase A1 member A; pla1a; PLA1A_HUMAN; PS PLA1; PS-PLA1; PSPLA 1; PSPLA1
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