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The antibody against PLA1A was raised in rabbit using the Recombinant Human Phospholipase A1 member A protein (293-398AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against PLA1A was raised in rabbit using the Recombinant Human Phospholipase A1 member A protein (293-398AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-05917A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PLA1A |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Biotin conjugated |
| Application | ELISA | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Phospholipase A1 member A protein (293-398AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q53H76 |
Uniprot Id
Q53H76
Target Species
Human
Target Name
PLA1A
Target Full Name
Phospholipase A1 member A
Target Function
Hydrolyzes the ester bond of the acyl group attached at the sn-1 position of phosphatidylserines (phospholipase A1 activity) and 1-acyl-2-lysophosphatidylserines (lysophospholipase activity) in the pathway of phosphatidylserines acyl chain remodeling. Cleaves phosphatidylserines exposed on the outer leaflet of the plasma membrane of apoptotic cells producing 2-acyl-1-lysophosphatidylserines, which in turn enhance mast cell activation and histamine production. Has no activity toward other glycerophospholipids including phosphatidylcholines, phosphatidylethanolamines, phosphatidic acids or phosphatidylinositols, or glycerolipids such as triolein.; Hydrolyzes lyso-PS but not PS.
Target Subcellular Location
Secreted.
Target Protein Families
AB hydrolase superfamily, Lipase family
Target Tissue Specificity
Widely expressed. Expressed in placenta, prostate and liver. Weakly or not expressed in skin, leukocytes, platelets, colon, spleen, lung, muscle and kidney.
Target Synonyms
AA986889; NMD; OTTHUMP00000215248; OTTHUMP00000215249; OTTHUMP00000215250; Phosphatidylserine specific phospholipase A1; Phosphatidylserine specific phospholipase A1alpha; Phosphatidylserine-specific phospholipase A1; Phospholipase A1 member A; pla1a; PLA1A_HUMAN; PS PLA1; PS-PLA1; PSPLA 1; PSPLA1
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