Rabbit anti-Human PLA2G12A Polyclonal Antibody

The antibody against PLA2G12A was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human PLA2G12A (NP_110448.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-04757A

Number

Cat.No	ADA-04757A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	PLA2G12A
Target Synonyms	GXII; ROSSY; PLA2G12; PLA2G12A	Form	Liquid
Species Reactivity	Human, Mouse	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	HeLa, HepG2, Mouse pancreas	Application	ELISA, WB

Cat.No

ADA-04757A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

PLA2G12A

Target Synonyms

GXII; ROSSY; PLA2G12; PLA2G12A

Form

Liquid

Species Reactivity

Human, Mouse

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

HeLa, HepG2, Mouse pancreas

Application

ELISA, WB

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PLA2G12A (NP_110448.2).	Target Species	Human
Immunogen Sequence	MALLSRPALTLLLLLMAAVVRCQEQAQTTDWRATLKTIRNGVHKIDTYLNAALDLLGGEDGLCQYKCSDGSKPFPRYGYKPSPPNGCGSPLFGVHLNIGI	Uniprot ID	Q9BZM1

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PLA2G12A (NP_110448.2).

Target Species

Human

Immunogen Sequence

MALLSRPALTLLLLLMAAVVRCQEQAQTTDWRATLKTIRNGVHKIDTYLNAALDLLGGEDGLCQYKCSDGSKPFPRYGYKPSPPNGCGSPLFGVHLNIGI

Uniprot ID

Q9BZM1

Background Information

Uniprot Id

Q9BZM1
Target Species

Human
Target Name

PLA2G12A
Target Full Name

Group XIIA secretory phospholipase A2
Target Function

PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. Does not exhibit detectable activity toward sn-2-arachidonoyl- or linoleoyl-phosphatidylcholine or -phosphatidylethanolamine.
Target Subcellular Location

Secreted. Cytoplasm.
Target Protein Families

Phospholipase A2 family
Target Tissue Specificity

Abundantly expressed in heart, skeletal muscle, kidney, liver and pancreas.
Target Research Area

Cardiovascular, Metabolism
Target Synonyms

EC 3.1.1.4 ; Group XII secreted phospholipase A2; Group XIIA secreted phospholipase A2; Group XIIA secretory phospholipase A2; Group XIIA secretory phospholipase A2 precursor ; GXII; GXII sPLA2; PG12A_HUMAN; phosphatidylcholine 2 acylhydrolase 12A; Phosphatidylcholine 2 acylhydrolase GXII ; Phosphatidylcholine 2-acylhydrolase 12A; Phospholipase A2 group XIIA; PLA2G12 ; Pla2g12a; ROSSY; sPLA2 XII; sPLA2-XII
Target Background

Secreted phospholipase A2 (sPLA2) enzymes liberate arachidonic acid from phospholipids for production of eicosanoids and exert a variety of physiologic and pathologic effects. Group XII sPLA2s, such as PLA2G12A, have relatively low specific activity and are structurally and functionally distinct from other sPLA2s (Gelb et al., 2000 [PubMed 11031251]).

Rabbit anti-Human PLA2G12A Polyclonal Antibody

Specifications

Immunogen Information

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